Curative effect observation of Shenqipollen tablet on deacclimatization during exposure period of the chronic intermittent hypoxia in high altitude regions

OBJECTIVE To investigate the intervention effects of Shenqi pollen tablets on deacclimatization during exposure period of chronic plateau intermittent hypoxic hypoxia. METHODS Selected 380 young healthy workers from the plains and low lying areas into the work area altitude 4 300m, with weekly indoor at an altitude of 4 300m for 5 working days, then returned to the elevation of 2 800m fixed base rest mode, continuously observed the intervention effect of Shenqi pollen tablets on symptom occurrence rate of plateau deacclimatization during rest period exposure period of 3 years in the highlands at an altitude of 2 800m. RESULTS The total detectable rate of altitude deacclimatization was 82.37% (313 / 380); the top 10 symptoms and the order were: lethargy ( 66.31% ) , fatigue ( 42.37% ) , dizziness ( 35.78% ) , insomnia ( 30.79% ) , decreased appetite (29.73%), upset (29.21%), general malaise (28.95%), depression (27.89%), palpitation (27.10%), and chest tightness (24.47% ). The crowd in need of treatment with altitude deacclimatization were detected in the total de-acclimation of those 34.18% (107 / 313). The intervention effect of Shenqi pollen tablets made the symptoms completely disappear in 92.52% (99 / 107) after medication of 15 days, recurrence rate (cured) was 78.79% (78 / 99) in who without continue medication in half of one year, even?there were some symptoms and self-medication to ease (CR) 21.21% (21 / 99), free remission or partial remission, but often needed medication (inactive) had 7.48% (8 / 107). There were no adverse drug reactions during observation period. CONCLUSION The high altitude deacclimatization during exposure period of chronic plateau intermittent hypoxic hypoxia has a higher prevalence. Shenqi pollen tablets have better short-term effect and long-term prevention, and is an effective disease prevention and treatment.