Clinicopathological Analysis of 308 cases Renal Biopsy

Objective To investigate the relationship between clinical manifestation and pathology, and clarify the clinical value of renal biopsy, in order to improve the diagnosis and treatment of chronic kidney disease. Methods 308 cases with renal biopsy were analyzed retrospectively, in cluding the relationship between pathological type and clinical type, hematuria, proteinuria. Results Primary glomerulonephritis(PGN)performanced with asymptomatic urinary abnormalities(AUA), nephritic syndrome(NiS), nephrotic syndrome(NS), acute renal failure(ARF) and chronic renal failure(CRF)were 18.8%, 25.2%, 42.8%, 7.2% and 6.0%. The performance in secondary glomerulonephritis(SGN)was 3.4%, 44.8%, 25.9%, 6.9% and 19.0%. The different performance between PGN and SGN in AUA, NIS, NS and CRF was statistically significant(P 0.05), yet in ARF was insignificant(P 0.05). PGN performanced with simple hematuria, a small amount of proteinuria, moderate proteinuria and heave proteinuria were 5.6%, 27.2%, 29.2% and 38.0%. The performance in SGN was 3.4%, 20.7%, 41.4% and 34.5%. There was no significant difference(P0.05) between PGN and SGN in hematuria and proteinuria. Conclusions NS is the most common type in PGN, and NIS is most popular for SGN. The heave proteinuria is the most common type in PGN, and moderate proteinuria is the most common type in SGN.