Studies on the Chemical Constituents of Lysimachia lobelioides Wall.
Xiaosheng Yang
Abstract
Xiaosheng Yang
Abstract
Objective To study the chemical constituents of Lysimachia lobelioides Wall..Methods The constituents of Lysimachia lobelioides Wall.were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography,and their structures were elucidated on the basis of spectroscopic evidence(MS,NMR).Results Thirteen compounds were obtained and identified as oleanolic acid(Ⅰ),13,28-epoxy-3,23-oleananediol-16-one(Ⅱ),12-oleanene-3,22-diol(Ⅲ),kaempferol-3-O-rutinoside(Ⅳ),kaempferol 3-O-(2,6-di-O-rhamnopyranosyl)-β-D-glucopyrano-side(Ⅴ),4',5,6,7-tetrahydroxyflavone(Ⅵ),ursolic acid(Ⅶ),lacceroic acid(Ⅷ),β-sitosterol(Ⅸ),daucosterol(Ⅹ),hexadecanoic acid(Ⅺ),sucrose(Ⅻ),chondrillasterol(ⅩⅢ).Conclusion All compounds the were obtained from this plant for the first time.
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Objective To study the chemical constituents of Lysimachia lobelioides Wall..Methods The constituents of Lysimachia lobelioides Wall.were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography,and their structures were elucidated on the basis of spectroscopic evidence(MS,NMR).Results Thirteen compounds were obtained and identified as oleanolic acid(Ⅰ),13,28-epoxy-3,23-oleananediol-16-one(Ⅱ),12-oleanene-3,22-diol(Ⅲ),kaempferol-3-O-rutinoside(Ⅳ),kaempferol 3-O-(2,6-di-O-rhamnopyranosyl)-β-D-glucopyrano-side(Ⅴ),4',5,6,7-tetrahydroxyflavone(Ⅵ),ursolic acid(Ⅶ),lacceroic acid(Ⅷ),β-sitosterol(Ⅸ),daucosterol(Ⅹ),hexadecanoic acid(Ⅺ),sucrose(Ⅻ),chondrillasterol(ⅩⅢ).Conclusion All compounds the were obtained from this plant for the first time.
Key concepts: Daucosterol, Oleanolic acid, Ursolic acid, Chemistry, Sephadex, Kaempferol, Silica gel, Chromatography