2009Lishizhen Medicine and Materia Medica ResearchRequires access

Studies on the Chemical Constituents of Lysimachia lobelioides Wall.

Xiaosheng Yang

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Abstract

Objective To study the chemical constituents of Lysimachia lobelioides Wall..Methods The constituents of Lysimachia lobelioides Wall.were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography,and their structures were elucidated on the basis of spectroscopic evidence(MS,NMR).Results Thirteen compounds were obtained and identified as oleanolic acid(Ⅰ),13,28-epoxy-3,23-oleananediol-16-one(Ⅱ),12-oleanene-3,22-diol(Ⅲ),kaempferol-3-O-rutinoside(Ⅳ),kaempferol 3-O-(2,6-di-O-rhamnopyranosyl)-β-D-glucopyrano-side(Ⅴ),4',5,6,7-tetrahydroxyflavone(Ⅵ),ursolic acid(Ⅶ),lacceroic acid(Ⅷ),β-sitosterol(Ⅸ),daucosterol(Ⅹ),hexadecanoic acid(Ⅺ),sucrose(Ⅻ),chondrillasterol(ⅩⅢ).Conclusion All compounds the were obtained from this plant for the first time.

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Objective To study the chemical constituents of Lysimachia lobelioides Wall..Methods The constituents of Lysimachia lobelioides Wall.were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography,and their structures were elucidated on the basis of spectroscopic evidence(MS,NMR).Results Thirteen compounds were obtained and identified as oleanolic acid(Ⅰ),13,28-epoxy-3,23-oleananediol-16-one(Ⅱ),12-oleanene-3,22-diol(Ⅲ),kaempferol-3-O-rutinoside(Ⅳ),kaempferol 3-O-(2,6-di-O-rhamnopyranosyl)-β-D-glucopyrano-side(Ⅴ),4',5,6,7-tetrahydroxyflavone(Ⅵ),ursolic acid(Ⅶ),lacceroic acid(Ⅷ),β-sitosterol(Ⅸ),daucosterol(Ⅹ),hexadecanoic acid(Ⅺ),sucrose(Ⅻ),chondrillasterol(ⅩⅢ).Conclusion All compounds the were obtained from this plant for the first time.

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Available abstract

Objective To study the chemical constituents of Lysimachia lobelioides Wall..Methods The constituents of Lysimachia lobelioides Wall.were isolated and purified by repeated silica gel and Sephadex LH-20 chromatography,and their structures were elucidated on the basis of spectroscopic evidence(MS,NMR).Results Thirteen compounds were obtained and identified as oleanolic acid(Ⅰ),13,28-epoxy-3,23-oleananediol-16-one(Ⅱ),12-oleanene-3,22-diol(Ⅲ),kaempferol-3-O-rutinoside(Ⅳ),kaempferol 3-O-(2,6-di-O-rhamnopyranosyl)-β-D-glucopyrano-side(Ⅴ),4',5,6,7-tetrahydroxyflavone(Ⅵ),ursolic acid(Ⅶ),lacceroic acid(Ⅷ),β-sitosterol(Ⅸ),daucosterol(Ⅹ),hexadecanoic acid(Ⅺ),sucrose(Ⅻ),chondrillasterol(ⅩⅢ).Conclusion All compounds the were obtained from this plant for the first time.

Key concepts: Daucosterol, Oleanolic acid, Ursolic acid, Chemistry, Sephadex, Kaempferol, Silica gel, Chromatography

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