Efficacy of Alprostadil injection and Shuganning injection on the treatment of chronic liver failure

Objective: To explore the efficacy of alprostadil injection and shuganning injection on the treatment of patients with chronic liver failure. Methods: Sixty patients with chronic liver failure were randomly divided into the treatment group( 30 cases) and the control group( 30 cases). On the basis of the control group,patients in the treatment group( 30 cases) were given Alprostadil injection combined with Shuganning injection,and patients in the control group( 30 cases) were given reduced glutathione,hepatocyte growth-promoting factors,plasma and human serum albumin,etc. The treatment course was 4 weeks. The alanine aminotransferase( ALT),total bilirubin( TBil),prothrombin activity( PTA),albumin( Alb) were observed,and to compare the total effective rate. Results: The total effective rate in the treatment group was 73. 3%,and in the control group was 46. 7%,there was significant difference between the two groups( P 0. 05). After treatment,there was significant difference in the level of ALT,TBil,PTA,Alb and the incidence rate of complications between the two groups( P 0. 05). Conclusions: Alprostadil injection and Shuganning injection are effective for treatment of chronic liver failure.