The research of lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig

To observe the distrbution characteristics of the lymphoid tissue in gastrointestinal mucosa of Guizhou miniature pig(Sus Scrofa domestica var.mino guizhounensis Yu.),the healthy and adult Guizhou miniature pigs were randomly selected,and the tissues of the gastrointestinal tract were collected,and then hematoxylin-eosin staining was used to observe and analyze the lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig.The result showed that the lymphocytes in gastrointestinal mucosa of Guizhou miniature pig were mainly located in lamina propria.The lymphocytes in small intestinal mucosa were highly significantly increased(P0.01) compared to that of in the gastric mucosa,showing upward trend from the duodenum to the ileum.There are many Peyer's patches observed in the lamina propria of ileum and submucosa.A decreasing trend was found from top to bottom in the lymphocytes of large intestinal mucosa(P0.01).The intraepithelial lymphocytes were found in all of the gastrointestinal mucosa,most of them were located in the small intestine,with a decreasing trend from the duodenum to the ileum.It was followed by the large intestine,at least in gastric mucosa.The results indicated that the lymphoid tissue distribution in gastrointestinal mucosa of Guizhou miniature pig was similar to that of in humans,mice,rats and other mammals.The highest density of lymphoid tissue was found in the small intestinal mucosa,the second in large intestinal mucosa and at least in the gastric mucosa.An upward trend was found in the lymphoid tissue of three sections of mucosa in the small intestine,and the highest density of lymphoid tissue was found in the ileum,with a decreasing trend in lymphoid tissue of large intestine.