Therapeutic effect of macular laser grid photocoagulation and intravitreal triamcinolone acetonide on diabetic macular edema

Objective To evaluate the clinical outcome of macular laser grid photocoagulation( MLGP) combined intravitreal triamc acetonide( IVTA) for diabetic macular edema( DME). Methods Sixty eyes of 48 patients with diabetic macular edema were randomly divided into three groups: the A group was treated with simple macular laser grid photocoagulation( n = 20); the B group was treated with intravitreal triamcinolone acetonide( IVTA)( n = 20); the C group was treated with macular laser grid photocoagulation 2 weeks after 4 mg IVTA. Then the visual acuity and macular thickness of the eyes in three groups were observed 1,3 and 6 months after treatment. Results The visual acuity, macular thickness of the eyes in three groups before treatment showed no significant difference( P 0. 05). The visual acuity,macular thickness of the eyes in group A,B were better after treatment,however there was no statistically significant difference( P 0. 05). The visual acuity and macular thickness of the eyes in group C were better than those of group A and B with significant differences( P 0. 05). Conclusions IVTA combined with macular laser grid photocoagulation is superior to simple laser photocoagulation and IVTA.( Chin J Ophthalmol and Otorhinolaryngol,2014, 14: 92-95)