2005•Chieh P'ou Hsueh PaoRequires access

EFFECT OF bFGF ON THE PROLIFERATION OF CULTURED OLFACTORY EPITHELIUM ENSHEATHING CELLS IN ADULT RAT

Jun Wang, Ke Wang, Yu Enhua, Changman Zhou

Abstract

Objective To investigate the effect of bFGF on the proliferation of olfactory epithelium ensheathing cells. Methods With BrdU incorporation method,the effect of bFGF on the proliferating rate of olfactory epithelium ensheathing cells was observed in the research. Results The olfactory epithelium ensheathing cells can proliferate without any proliferating factor.The bFGF(10μg/L)can enhance the proliferating rate in a moderate way.In this experiment BPE(bovine pituitary extract) can not enhance the stimulating effect of bFGF.Conclusion The bFGF(10μg/L)can stimulate the proliferating rate of the olfactory epithelium ensheathing cells in vitro.

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Available abstract

Key concepts: Olfactory ensheathing glia, Olfactory epithelium, Basic fibroblast growth factor, Epithelium, Cell biology, Olfactory system, Olfactory nerve, Olfactory mucosa