Efficacy and safety of the low molecular weight heparin and mailuoshutong to prevent deep venous thrombosis

Objective To Observe the efficacy and safety of with mailuoshutong and low molecular weight heparin to prevent lower extremity deep venous thrombosis for total knee and hip arthroplasty.Methods From June 2006 to August 2009,88 cases of total hip and 85 cases of total knee arthroplasty inpatients were randomly divided into experimental group and control group.Epidural analgesia pump was used to relieve pain after operation.In order to prevent DVT,Oral Mailuoshutong was used on the first day after operation and low molecular weight heparin on the third day after pulling epidural Pump.Low molecular weight heparin was used to prevent DVT on the third day after pulling epidural Pump.Results The incidence of DVT for patients in experimental group was 3.3%(3/91).The incidence of DVT for patients in control group was 11.0%(9/82).There was significant Difference between the two groups(χ2=3.940,P0.05).The incidence of adverse reactions with bleeding in experiment patients was 6.6%,and 6.1% in control group patients.There was in-significant Difference between the two groups(χ2=0.018,P0.05).Conclusion It is safe,feasible and effective to prevent DVT for total hip and knee replacement patients,who used mailuoshutong on the first day and low molecular weight hep-arin on the third day after operation