Clinical investigation and analysis of pathogenic fungus on 305 cases of onychomycosis in Nanjing

Objective To survery the epidemiology of pathogenic fungi and clinical patterns of onychomycosis during Mar 2011 to Apr 2012 in Nanjing district. Methods Fungal culture and clinical analysis were performed on 305 cases of onychomycosis with positive direct microscopic examination. Results 165 strains of pathogens were isolated, the positive rate was 54.1%. The most frequently isolated fungus was dermatophytes(91%), followed by non-dermatophytic moulds(4.8%) and yeasts(4.2%). DLSO were the most frequently clinical patterns(48.2%), followed by SWO(24.9%) and TDO(23.3%). Conclusion In Nanjing district, the most frequently pathogenic fungus of onychomycosis was trichophyton rubrum and the most frequently clinical patterns was DLSO.