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Use of Murine L5178Y Lymphoma Thymidine Kinase Mutants for in Vitro and in Vivo Antitumour Efficacy Evaluation of Novel Thymidylate Synthase Inhibitors

T C Stephens, Marie-Louise Smith, S. E. Waterman, Manabu McCloskey, Ann L. Jackman, F. T. Boyle

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Key concepts: Thymidylate synthase, Thymidine kinase, Thymidine, Nucleotide salvage, Nucleoside, In vivo, Biochemistry, In vitro

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Use of Murine L5178Y Lymphoma Thymidine Kinase Mutants for in Vitro and in Vivo Antitumour Efficacy Evaluation of Novel Thymidylate Synthase Inhibitors — Research Paper | ScholarLens