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A Two_Day Course of Compound Dihydroartemisinin for Falciparum Malaria: A Report of 50 Cases

Song Jian-ping

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Abstract

A trial of compound dihydroartemisinin was carried out in 50 acute falciparum malaria patients without complications. The patients received a total dosage of 8 tablets of compound dihydroartemisinin for 2 days. Forty_six patients had a complete 28_day follow_up period. No recrudescence was observed. The mean fever_subsidence time and mean parasite clearance time were ( 17.2±9.9 ) hours and ( 52.0±20.2 ) hours respectively. Indexes of hematology, ALT, AST and total bilirubin were examined in 34 patients on the first day of treatment (D0) and the seventh day (D7). The above examinations appeared abnormal in some cases on D0 but returned normal on D7.

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What this paper is about

A trial of compound dihydroartemisinin was carried out in 50 acute falciparum malaria patients without complications. The patients received a total dosage of 8 tablets of compound dihydroartemisinin for 2 days. Forty_six patients had a complete 28_day follow_up period. No recrudescence was observed. The mean fever_subsidence time and mean parasite clearance time were ( 17.2±9.9 ) hours and ( 52.0±20.2 ) hours respectively. Indexes of hematology, ALT, AST and total bilirubin were examined in 34 patients on the first day of treatment (D0) and the seventh day (D7). The above examinations appeared abnormal in some cases on D0 but returned normal on D7.

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Available abstract

A trial of compound dihydroartemisinin was carried out in 50 acute falciparum malaria patients without complications. The patients received a total dosage of 8 tablets of compound dihydroartemisinin for 2 days. Forty_six patients had a complete 28_day follow_up period. No recrudescence was observed. The mean fever_subsidence time and mean parasite clearance time were ( 17.2±9.9 ) hours and ( 52.0±20.2 ) hours respectively. Indexes of hematology, ALT, AST and total bilirubin were examined in 34 patients on the first day of treatment (D0) and the seventh day (D7). The above examinations appeared abnormal in some cases on D0 but returned normal on D7.

Key concepts: Dihydroartemisinin, Medicine, Malaria, Plasmodium falciparum, Gastroenterology, Internal medicine, Bilirubin, Surgery

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