Analysis on characteristics by continuous glucose monitoring system in pregnant women with gestational diabetes mellitus

Objective To analyze the characteristics in pregnant women between gestational diabetes mellitus(GDM) and pregnant women with glucose profile of normal sugar tolerance by continuous glucose monitoring system(CGMS).Methods Enrolled first pregnant women on regular check during Jun.2009-May 2010 were then dividing into two groups by the result of oral glucose tolerance test(OGTT).The parameters of CGMS were assessed on them.Results There were significant differences in mean amplitude of glycemic excursions(3.5±1.0) mmol/L vs(2.4±0.3) mmol/L,largest amplitude of glycemic excursions(5.2±1.6) mmol/L vs(4.3±1.1) mmol/L,the 1 h mean blood glucose after breakfast(7.1±1.1)mmol/L vs(5.9±0.6) mmol/L,postprandial peak glucose of breakfast(8.5±1.1) mmol/L vs(6.8±1.1) mmol/L,the time to peak of breakfast(57.4±15.5) min vs(45.3±14.8) min.All the differences were significant in comparisons(all P0.01).Conclusion There were fluctuations in blood glucose in GDM patients.CGMS could discover gestational diabetes mellitus,guiding clinical work.