Expression of β-catenin on the Eyelash Follicle in Bovine Embryo Development

To study expression of β-catenin in the development of eyelash follicle in mammalian,24 bovine embryoes are used as experimental animal material.Paraffin-embeded tissues from normal bovine embryonic upper eyelid skin are dyed by IHC(Immune histochemical method) with anti-β-catenin antibody,β-catenin expression level of different developmental stage in embryonic bovine eyelash follicle are analyzed.β-catenin is detected in the placode,hair bud and hair peg during the early and middle stage of bovine eyelash follicle development,bulge and matrix are strongly positive;Bulge,the outer and inner root sheath close to bulge are strongly positive while expression of β-catenin in the matrix decrease during the late stage of eyelash follicle developmental and maturing stage.The result suggest that β-catenin play an important role in eyelash follicle morphogenesis.