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2004•Journal of Shanxi Medical College for Continuing EducationRequires access

The Diagnostic Value of Associated Detection of Anti-Tuberculosis Antibody,DNA and Tuberculin Test in Pulmonary Tuberculosis with Negative Spuntumcultivations

Jia Jun

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Abstract

Objective:To study the diagnostic value of combined serum anti tuberculosis antibody(LAM),PCR and PPD 5 IU intradermal injection test in detecting pulomonary tuberculosis with negative spuntumcultivations.Methods:The three methods were used to detect 42 pulmonary tuberculosis patients with negative spuntumcultivations,46 pulmonary tuberculosis with positive bacillus and 36 normal persons.Results:The sensitivity and specificity of a single test were as follows:LAM 67.4%,94.4%;PCR 95.7%,97.2%;PPD 56.5%,97.2%;and the detection rate of a single test were as follows:PCR 47.6%,LAM 31.0%,PPD 21.4%.The detection rate of combined method was obviously higher than that of the single test and its specificity was more than 90%.Conclusion:The combination had an increased detection rate and better specificity in detecting pulmonary tuberculosis with negative spuntumcultivations.

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What this paper is about

Objective:To study the diagnostic value of combined serum anti tuberculosis antibody(LAM),PCR and PPD 5 IU intradermal injection test in detecting pulomonary tuberculosis with negative spuntumcultivations.Methods:The three methods were used to detect 42 pulmonary tuberculosis patients with negative spuntumcultivations,46 pulmonary tuberculosis with positive bacillus and 36 normal persons.Results:The sensitivity and specificity of a single test were as follows:LAM 67.4%,94.4%;PCR 95.7%,97.2%;PPD 56.5%,97.2%;and the detection rate of a single test were as follows:PCR 47.6%,LAM 31.0%,PPD 21.4%.The detection rate of combined method was obviously higher than that of the single test and its specificity was more than 90%.Conclusion:The combination had an increased detection rate and better specificity in detecting pulmonary tuberculosis with negative spuntumcultivations.

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Available abstract

Objective:To study the diagnostic value of combined serum anti tuberculosis antibody(LAM),PCR and PPD 5 IU intradermal injection test in detecting pulomonary tuberculosis with negative spuntumcultivations.Methods:The three methods were used to detect 42 pulmonary tuberculosis patients with negative spuntumcultivations,46 pulmonary tuberculosis with positive bacillus and 36 normal persons.Results:The sensitivity and specificity of a single test were as follows:LAM 67.4%,94.4%;PCR 95.7%,97.2%;PPD 56.5%,97.2%;and the detection rate of a single test were as follows:PCR 47.6%,LAM 31.0%,PPD 21.4%.The detection rate of combined method was obviously higher than that of the single test and its specificity was more than 90%.Conclusion:The combination had an increased detection rate and better specificity in detecting pulmonary tuberculosis with negative spuntumcultivations.

Key concepts: Medicine, Tuberculosis, Tuberculin, Pulmonary tuberculosis, Mycobacterium tuberculosis, Internal medicine, Immunology, Gastroenterology

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The Diagnostic Value of Associated Detection of Anti-Tuberculosis Antibody,DNA and Tuberculin Test in Pulmonary Tuberculosis with Negative Spuntumcultivations — Research Paper | ScholarLens