2006•International Journal of Dermatology and VenereologyRequires access

Virulence Factors of Candida albicans

Liu Wei-d

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Abstract

Candida albicans is an important human fungal pathogen. We review the virulence factors of Candida albicans and their identification. The factors include adhesion molecules, enzymes for invasion, and factors responsible for morphogenesis and phenotypic switching of Candida albicans, etc. They may be detected by Ura-blaster methodology, gene splitting, analysis of gene function with systematic approaches and search of genes potentially related to virulence by differential-display reverse transcription polymerase chain reaction.

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What this paper is about

Candida albicans is an important human fungal pathogen. We review the virulence factors of Candida albicans and their identification. The factors include adhesion molecules, enzymes for invasion, and factors responsible for morphogenesis and phenotypic switching of Candida albicans, etc. They may be detected by Ura-blaster methodology, gene splitting, analysis of gene function with systematic approaches and search of genes potentially related to virulence by differential-display reverse transcription polymerase chain reaction.

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Available abstract

Candida albicans is an important human fungal pathogen. We review the virulence factors of Candida albicans and their identification. The factors include adhesion molecules, enzymes for invasion, and factors responsible for morphogenesis and phenotypic switching of Candida albicans, etc. They may be detected by Ura-blaster methodology, gene splitting, analysis of gene function with systematic approaches and search of genes potentially related to virulence by differential-display reverse transcription polymerase chain reaction.

Key concepts: Virulence, Candida albicans, Biology, Microbiology, Gene, Corpus albicans, Pathogen, Virulence factor

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