2009•Chinese Journal of New Clinical MedicineRequires access

Clinical study of cytokine-induced killer cells in the treatment of patients with advanced malignant tumor after chemotherapy

Guan Hong-me

Abstract

Objective To estimate the clinical effects in the treatment of patients with advanced malignant tumor with cytokine-induced killer(CIK)cells.Methods CIK cells were induced with IL-2.γ-IFN.anti-CD3 monoclonal antibody and IL-1,then were transfused back to the patients with advanced malignant tumor after two weeks,for observation of effects,life quality,PFS,toxic reaction and the Karnofsky's grade.Results The effective rate and survival period of CIK group were significantly higher than that of control group.Conclusion CIK cells therapy can enhance effect of the anti-cancer,improve survival quantity and prolong survival period,which probably can provide a potent immune therapeutic strategy for patients with advanced malignant tumor.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Medicine, Cytokine-induced killer cell, Chemotherapy, Immunotherapy, Monoclonal antibody, Oncology, Cytokine, Immune system