2002•Pharmaceutical Journal of Chinese People's Liberation ArmyRequires access

Determination of Ephedrine Hydrochloride in Compound Nasal Spray by Spectrophotometry

Rui Wang

Abstract

Aim To determine the Ephedrine Hydrochloride content in Compound Nasal Spray.Methods To use Spectrophotometry to measure the content with detective wavelength at 569nm.Results The calibration curve is linear in the range of 4.13～41.26μg·ml -1 (r=0.999 7) for Ephedrine Hydrochloride.The average recovery was 99.57% with RSD=0.38%(n=6).Conclusion The method is simple,quick and accurate for the determination of Ephedrine Hydrochloride in Compound Nasal Spray.

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Key concepts: Ephedrine, Chromatography, Calibration curve, Chemistry, Hydrochloride, Spectrophotometry, Linear relationship, Nasal spray