ScholarLens Back to search
1984•Yaoxue xuebaoRequires access

ANTI-SRS-A EFFECT OF TETRANDRINE

Hong Zhang

Open publisher page 0 citations

Abstract

Tetrandrine was shown to significantly inhibit the contraction of guinea pig tracheal or lung strips induced by SRS-A 100 U/ml in vitro. It was also found to inhibit the contractile effect on human bronchial or lung strips induced by SRS-A U/ml in vitro.Tetrandrine 25 mg/kg given intravenously prior to SRS-A antagonized the augmentation of respiratory airflow by SRS-A.The SRS-A induced asthmatic attack of guinea pig was also alleviated by tetrandrine. The anti-SRS-A effect of tetrandrine was reduced when the extracellular Ca~(++) level was elevated and vice versa.

About this research paper

What this paper is about

Tetrandrine was shown to significantly inhibit the contraction of guinea pig tracheal or lung strips induced by SRS-A 100 U/ml in vitro. It was also found to inhibit the contractile effect on human bronchial or lung strips induced by SRS-A U/ml in vitro.Tetrandrine 25 mg/kg given intravenously prior to SRS-A antagonized the augmentation of respiratory airflow by SRS-A.The SRS-A induced asthmatic attack of guinea pig was also alleviated by tetrandrine. The anti-SRS-A effect of tetrandrine was reduced when the extracellular Ca~(++) level was elevated and vice versa.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Tetrandrine was shown to significantly inhibit the contraction of guinea pig tracheal or lung strips induced by SRS-A 100 U/ml in vitro. It was also found to inhibit the contractile effect on human bronchial or lung strips induced by SRS-A U/ml in vitro.Tetrandrine 25 mg/kg given intravenously prior to SRS-A antagonized the augmentation of respiratory airflow by SRS-A.The SRS-A induced asthmatic attack of guinea pig was also alleviated by tetrandrine. The anti-SRS-A effect of tetrandrine was reduced when the extracellular Ca~(++) level was elevated and vice versa.

Key concepts: Tetrandrine, Guinea pig, Contraction (grammar), In vitro, Pharmacology, Chemistry, Lung, Respiratory system

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
ANTI-SRS-A EFFECT OF TETRANDRINE — Research Paper | ScholarLens