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2013•Journal of Clinical Pulmonary MedicineRequires access

Value of serum procalcitonin in the differentiation of causes of pleural exudates

Chen Xiao

Open publisher page 1 citations

Abstract

Objective To investigate the relationship between serum procalcitonin(PCT) and the causes of pleural exudates.Methods 70 patients with pleural exudates were given serum PCT assay within 12 hours.Results The average PCT levels of patients with tuberculosis pleurisy,parapneumonic effusion,empyema,malignant effusion and rheumatoid arthritis-associated pleural effusion were(0.052 ±0.006) ng/ml,(0.224 ±0.223) ng/ml,(3.230 ±4.517) ng/ml,(0.073 ±0.031) ng/ml,and 0.115 ng/ml respectively.There were significant differences among the groups(Nonparametric test: χ2 = 47.111,P 0.001).Patients with empyema were well distinguished from others using cut-off PCT values of ≥0.295 ng / ml(sensitivity: 0.909,specificity: 0.949).Conclusion Serum level of PCT can separate different causes of pleural exudates.

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What this paper is about

Objective To investigate the relationship between serum procalcitonin(PCT) and the causes of pleural exudates.Methods 70 patients with pleural exudates were given serum PCT assay within 12 hours.Results The average PCT levels of patients with tuberculosis pleurisy,parapneumonic effusion,empyema,malignant effusion and rheumatoid arthritis-associated pleural effusion were(0.052 ±0.006) ng/ml,(0.224 ±0.223) ng/ml,(3.230 ±4.517) ng/ml,(0.073 ±0.031) ng/ml,and 0.115 ng/ml respectively.There were significant differences among the groups(Nonparametric test: χ2 = 47.111,P 0.001).Patients with empyema were well distinguished from others using cut-off PCT values of ≥0.295 ng / ml(sensitivity: 0.909,specificity: 0.949).Conclusion Serum level of PCT can separate different causes of pleural exudates.

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Available abstract

Objective To investigate the relationship between serum procalcitonin(PCT) and the causes of pleural exudates.Methods 70 patients with pleural exudates were given serum PCT assay within 12 hours.Results The average PCT levels of patients with tuberculosis pleurisy,parapneumonic effusion,empyema,malignant effusion and rheumatoid arthritis-associated pleural effusion were(0.052 ±0.006) ng/ml,(0.224 ±0.223) ng/ml,(3.230 ±4.517) ng/ml,(0.073 ±0.031) ng/ml,and 0.115 ng/ml respectively.There were significant differences among the groups(Nonparametric test: χ2 = 47.111,P 0.001).Patients with empyema were well distinguished from others using cut-off PCT values of ≥0.295 ng / ml(sensitivity: 0.909,specificity: 0.949).Conclusion Serum level of PCT can separate different causes of pleural exudates.

Key concepts: Medicine, Procalcitonin, Empyema, Gastroenterology, Parapneumonic effusion, Internal medicine, Pleural effusion, Rheumatoid arthritis

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