Significance of serum HDL-C,LDL-C,LDL-C/HDL-C ratio levels in middle-and elderly-aged patients with coronary heart disease

Objective To appraise the significance of serum high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C) and low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio(LDL-C/HDL-C) in middle-and elderly-aged patients with coronary heart disease(CHD).Methods Association between HDL-C,LDL-C and LDL-C/HDL-C ratio and coronary artery lesions were analyzed in 290 patients who underwent coronary arteriongraphy,including coronary atherosclerosis diagnosed in 83 patients,given drug treatment,CHD confirmed in 163 patients who took PCI and negative in 44 cases as control group.And the differences among the three groups of males and females in blood lipid levels were analyzed.Results The levels of total cholesterol(TC),LDL-C and LDL-C/HDL-C ratio among the three groups were statistically different(P0.05 or 0.01).Stent group had higher TC,LDL-C,TC to HDL-C ratio(TC/HDL-C) than drug treatment group and controls(P0.05 or 0.01).Stent group had significantly lower HDL-C than drug treatment group and controls(P0.05).HDL-C level of females in drug treatment group was significantly higher than that of males(P0.01),but TC/HDL-C and LDL-C/HDL-C ratios of females in controls were lower than those of males(P0.05).TC and HDL-C levels of females in stent group were higher than those males(P0.05).TC and HDL-C levels of females in controls were higher than those of males(P0.05),but TG/HDL-C and LDL-C/HDL-C of females decreased more than those of males(P0.05).Conclusion Serum HDL-C,LDL-C and LDL-C/HDL-C ratio associated with coronary artery lesions,and they were useful predicting indexes of clinical diagnosis and treatment for middle-and elderly-aged CHD patients.