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2002•Zhongguo dangdai erke zazhiRequires access

Level of Exhaled Nitric Oxide in Asthmatic Children

Hu Xiao

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Abstract

Objective To investigate the level of exhaled nitric oxide (NO) in children with asthma. Methods In 34 asthmatic children (aged 6～14 years) and 36 non respiratory disease subjects, exhaled NO with 13～15 cmH 2O expiratory airway pressure was measured by the chemiluminescent NO analyzer of the online method and the FEV 1 % was measured by a pocket spirometer at the same time. Results The level of exhaled NO of asthmatic children was significantly higher than that of the non respiratory disease subjects [( 89.4 ± 56.4 ) ppb vs ( 15.8 ± 5.8 ) ppb](P 0.01 ). There was no significant correlation between exhaled NO and FEV 1% in asthmatic children (r= 0.06 ,P 0.05 ). Conclusions The level of exhaled NO in asthmatic children is higher than that of normal subjects.

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What this paper is about

Objective To investigate the level of exhaled nitric oxide (NO) in children with asthma. Methods In 34 asthmatic children (aged 6～14 years) and 36 non respiratory disease subjects, exhaled NO with 13～15 cmH 2O expiratory airway pressure was measured by the chemiluminescent NO analyzer of the online method and the FEV 1 % was measured by a pocket spirometer at the same time. Results The level of exhaled NO of asthmatic children was significantly higher than that of the non respiratory disease subjects [( 89.4 ± 56.4 ) ppb vs ( 15.8 ± 5.8 ) ppb](P 0.01 ). There was no significant correlation between exhaled NO and FEV 1% in asthmatic children (r= 0.06 ,P 0.05 ). Conclusions The level of exhaled NO in asthmatic children is higher than that of normal subjects.

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Available abstract

Objective To investigate the level of exhaled nitric oxide (NO) in children with asthma. Methods In 34 asthmatic children (aged 6～14 years) and 36 non respiratory disease subjects, exhaled NO with 13～15 cmH 2O expiratory airway pressure was measured by the chemiluminescent NO analyzer of the online method and the FEV 1 % was measured by a pocket spirometer at the same time. Results The level of exhaled NO of asthmatic children was significantly higher than that of the non respiratory disease subjects [( 89.4 ± 56.4 ) ppb vs ( 15.8 ± 5.8 ) ppb](P 0.01 ). There was no significant correlation between exhaled NO and FEV 1% in asthmatic children (r= 0.06 ,P 0.05 ). Conclusions The level of exhaled NO in asthmatic children is higher than that of normal subjects.

Key concepts: Exhaled nitric oxide, Medicine, Spirometer, Asthma, Internal medicine, Respiratory system, Airway, Exhaled air

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