Synthesis and biological activity of N-substituted- 5-sulfonyl pyrazole oxime ester derivatives

Objective To obtain novel pyrazole derivatives which have higher biological activity. Methods New pyrazole compounds were synthesized with pyrazolone, thiophenol and hydroxylamine hydrochloride. And its structures were established by spectrum and its biological activities were detected. Results Five new compounds were designed and synthesized, which was not reported in other papers. Also their structures were established by IR, 1H NMR, and elemental analysis. Conclusions Preliminary bioassays indicated that some compounds showed fungicidal activity.