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CLINICAL OBSERVATION ON THE ANALGESIC EFFICACY OF TRANSDERMAL FENTANYL FOR MODERATE OR SEVERE CANCER PAIN

Jiaxin Du

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Abstract

Objective:To observe the analgesic efficacy of transdermal fentanyl on late cancer pain. Methods:One hundred and twenty patients with moderate or severe cancer pain were treated with transdermal fentanyl. For the patients who had not been treated before,the initial dosage of transdermal fentanyl started from 25 μg·h~ -1 ;for those who had been treated with morphine before,the initial dosage was arranged according to the individual cases. Results:The overall effective rate was 95.0%(114/120);the complete and marked effective rates were 80.0%(96/120)and 15.0%(18/120),respectively. Conclusion:The therapeutic effiect of transdermal fentanyl is stable and the adverse effect is mild. It can be used as a substitute for oral strong opioids in clinic.

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Objective:To observe the analgesic efficacy of transdermal fentanyl on late cancer pain. Methods:One hundred and twenty patients with moderate or severe cancer pain were treated with transdermal fentanyl. For the patients who had not been treated before,the initial dosage of transdermal fentanyl started from 25 μg·h~ -1 ;for those who had been treated with morphine before,the initial dosage was arranged according to the individual cases. Results:The overall effective rate was 95.0%(114/120);the complete and marked effective rates were 80.0%(96/120)and 15.0%(18/120),respectively. Conclusion:The therapeutic effiect of transdermal fentanyl is stable and the adverse effect is mild. It can be used as a substitute for oral strong opioids in clinic.

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Available abstract

Objective:To observe the analgesic efficacy of transdermal fentanyl on late cancer pain. Methods:One hundred and twenty patients with moderate or severe cancer pain were treated with transdermal fentanyl. For the patients who had not been treated before,the initial dosage of transdermal fentanyl started from 25 μg·h~ -1 ;for those who had been treated with morphine before,the initial dosage was arranged according to the individual cases. Results:The overall effective rate was 95.0%(114/120);the complete and marked effective rates were 80.0%(96/120)and 15.0%(18/120),respectively. Conclusion:The therapeutic effiect of transdermal fentanyl is stable and the adverse effect is mild. It can be used as a substitute for oral strong opioids in clinic.

Key concepts: Transdermal, Fentanyl, Medicine, Cancer pain, Analgesic, Anesthesia, Adverse effect, Transdermal patch

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CLINICAL OBSERVATION ON THE ANALGESIC EFFICACY OF TRANSDERMAL FENTANYL FOR MODERATE OR SEVERE CANCER PAIN — Research Paper | ScholarLens