2005•Journal of Zhengzhou UniversityRequires access

Expression of HGF and its receptor C-Met in breast cancer tissue

Wang Yuping

Abstract

Aim: To study the expression of HGF and its receptor C-Met in the breast cancer tissue and its prognostic value. Methods: The expression of HGF and C-Met in 39 cases of invasive ductal breast carcinoma and 12 cases of breast fibroadenoma was detected using immunohistochemistry. Results: In invasive ductal breast carcinoma tissue, the expression of HGF and C-Met was much higher than those in breast fibroadenoma tissue(P0.05). The expression of HGF and C-Met was positively correlated with histological differentiation and PTNM classification. Conclusion: The overexpression of HGF and C-Met in breast cancer tissue may correlate with the patients' had prognosis.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Fibroadenoma, Immunohistochemistry, Breast cancer, Medicine, Ductal carcinoma, Invasive ductal carcinoma, Breast Fibroadenoma, Breast tissue