A study on large granular lymphocyte and lymphocyte micronuclei in peripheral blood of lymphomas patients

Objective To study the variety and signifecance about large granular lymphocyte(LGL) and lymphocyte micronuclei in peripheral blood of lymphomas patients. Methods Peripheral blood smears of 15 cases lymphpmas patients and 20 cases blood donor ,were stained by Wrights method and examined by light microscopy. Results The peripheral blood of lymphomas patients large granular lymphocyte percentage is 24.01%±7.51%, matched control LGL percentage is 5.65%±2.60%, the difference have to show(P0.001). The peripheral blood of lymphomas patients lymphocyte micronuclei rate is 0.87‰, matdhed control is 0.65‰(P0.05). Conclusions The lymphoma get the clinical significance that machines immunity appearance and prognosis.