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2001•The Chinese Journal of Clinical PharmacologyRequires access

Drug Interaction Related to CYP3A4

Peng Hua

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Abstract

Cytochrome P450 3A4(CYP3A4) is an important hepatic drug metabolic enzyme which is responsible for the metabolism of a large number of substrates such as endogenous and exogenous compounds (especially drugs). CYP3A4 plays a critical role in metabolism of many clinical drugs. Drug interactions related to CYP3A4 are very common. The article reviews drug interaction related to CYP3A4.

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What this paper is about

Cytochrome P450 3A4(CYP3A4) is an important hepatic drug metabolic enzyme which is responsible for the metabolism of a large number of substrates such as endogenous and exogenous compounds (especially drugs). CYP3A4 plays a critical role in metabolism of many clinical drugs. Drug interactions related to CYP3A4 are very common. The article reviews drug interaction related to CYP3A4.

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Available abstract

Cytochrome P450 3A4(CYP3A4) is an important hepatic drug metabolic enzyme which is responsible for the metabolism of a large number of substrates such as endogenous and exogenous compounds (especially drugs). CYP3A4 plays a critical role in metabolism of many clinical drugs. Drug interactions related to CYP3A4 are very common. The article reviews drug interaction related to CYP3A4.

Key concepts: CYP3A4, Drug metabolism, Cytochrome P450, Drug, Pharmacology, Chemistry, Metabolism, Medicine

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