2011•Huaxi yixueRequires access

Analysis of Effectiveness and Drug Resistance in Patients with AIDS Receiving Highly Active Antiretroviral Therapy

Liang Cheng

Abstract

Objective To evaluate the efficacy of highly active antiretroviral therapy(HAART) in treating HIV,and observe the resistance of HAART in AIDS patients.Methods Twenty-three HIV patients receiving free HAART for one to three years were investigated.The plasma viral load,drug resistance to HIV-1,CD4+ T cell count were tested and routine laboratory examinations were performed in our study.Results After one to fhnee-year HAART treatment,HIV viral load of six patients(26.1%) declined to the undetectable level,while the viral load of 17 patients(73.9%) kept at a high level.Resistance to HIV-1 occurred in five cases(21.7%).Only nine patients(39.1%) had good treatment compliance.Conclusion HAART has a poor therapeutic effect on patients with HIV/AIDS with a high rate of drug resistance and poor treatment compliance.

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Key concepts: Medicine, Viral load, Drug resistance, Antiretroviral therapy, Internal medicine, HIV drug resistance, Drug, Human immunodeficiency virus (HIV)