Malignant or clonal diseases evoluted from aplastic anemia
Zonghong Shao
Abstract
Zonghong Shao
Abstract
Aplastic anemia(AA)is one of the bone marrow failure diseases.It was found that some AA cases were with risks to evolute to malignant or clonal diseases.The mechanism of the evolution might include hematopoietic stem cell defection,marrow microenvironent disorder,treatment interferes and so on.
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Aplastic anemia(AA)is one of the bone marrow failure diseases.It was found that some AA cases were with risks to evolute to malignant or clonal diseases.The mechanism of the evolution might include hematopoietic stem cell defection,marrow microenvironent disorder,treatment interferes and so on.
Key concepts: Aplastic anemia, Medicine, Bone marrow failure, Haematopoiesis, Bone marrow, Anemia, Somatic evolution in cancer, Immunology