2006•Journal of Oral Science ResearchRequires access

Clear Cell Carcinoma of Salivary Gland: An Immunohistochemiacal Study of 8 Cases

Xianghua Chen

Abstract

Objective: To study the origination and biologic features of clear cell carcinoma of salivary glands(CCCs).Methods: 8 cases CCCs were indentified and studied by literature and immunohistochemistry.Results: Immunohistochemically,EMA and CK8 were positive in all cases.CK18 and CK-HMW were positive in 2 cases,respectively.S-100 was positive in 1 case.Calponin,SMA and p53 were negative in all cases.The positive rate of PCNA were 72.25%.Conclusion: Clear cell carcinoma of salivary gland is adeno-epithelial neoplasms,with higher rate of proliferation.It is lower grade maglignance.

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Key concepts: Immunohistochemistry, Calponin, Salivary gland, Proliferating cell nuclear antigen, Pathology, Carcinoma, Medicine, Clear cell