2011•Jiangsu Medical JournalRequires access

The evalue of detecting nitric oxide in diagnosis and evaluation of therapeutic efficacy in patients with bronchial asthma

Huang Ma

Abstract

Objective To investigate the evalue of detecting exhaled nitric oxide(FENO) in diagnosis and evaluation of therapeutic efficacy in patients with bronchial asthma.Methods FENO was measured by nitric oxide analyzer in 72 outpatients with asthma[(11 cases with controlled asthma(group A),30 cases with partly controlled asthma(group B) and 31 cases with uncontrolled asthma(group C)] and 57 healthy people(group D).Results The concentrations of FENO in groups of A,B and C were (33.5±22.3)ppb,(40.8±16.0)ppb and(78.0±31.5)ppb,respectively,which were significantly higher than(17.2±11.4)ppb in group D(P0.01).The concentration of FENO was lower in groups of A and B than that in group C(P0.01).Conclusion FENO examination may be helpful in the diagnosis and evaluation of therapeutic efficacy in patients with asthma.

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Key concepts: Exhaled nitric oxide, Asthma, Medicine, Group B, Nitric oxide, Group A, Internal medicine, Gastroenterology