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Interferon Regulatory Factor Family

Chen Han-chun

Abstract

Interferon regulatory factors (IRFs) are some of important transcriptional factors for regulating the expression of interferon (IFN) and interferon stimulated genes (ISG) as well as the genes related to IFN signal transduc-tion.The multiple biological effects of the members of interferon regulatory factor family have been shown to be mediated by the transcriptional activation for IFN, ISG and the related genes.

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Available abstract

Key concepts: Interferon regulatory factors, Interferon, IRF8, IRF1, Gene, Biology, Transcriptional regulation, Transcription factor