Diagnostic significance of the antibody detection of mycobacterium tuberculosis to tuberculous pleurisy

Objective To evaluate the antibody detection of TB-SA in the diagnosis of patients with tuberculous pleurisy.Methods 121 patients with tuberculous pleurisy and 30 patients with non-tuberculosis pleurisy were selected in this study,and the antibodies of TB-SA in their pleural fluid and serum were detected by enzyme linked immunosorbent assay(ELISA).Results The sensitivities of TB-SA antibody were 68.60% in pleural fluid and 33.38% in serum respectively in the tuberculous pleurisy group,while the sensitivities in pleural fluid and serum were 96.67% both in the non-tuberculous pleurisy group.The sensitivity difference of TB-SA antibody between pleural fluid and serum in the tuberculous pleurisy group had statistical significance(P0.05).Conclusion The antibody detection of TB-SA in pleural fluid and serum shows an acceptable sensitivity and magnificent specificity in the diagnosis of tuberculous pleuritis,which has a better reference value in the differential diagnosis of tuberculous pleurisy.