Study on Expression of Synaptophysin SVP_([38]) and Development in Chicken Cerebellum

Immunohisto-chemical SP method was used to investigate the expression of synaptophysin SVP_([38]) in chicken cerebellum of E_(15), E_(20) and P_(10). The results showed that SVP_([38])-IR product presented as different forms: particles, dots, positive neurons and positive nerve fibers; There are three changing trends in the density of SVP_([38])-IR product in cerebellum: (1)keeping constant in molecular layer, granular layer, nucleus cerebellaris intermedius, nucleus cerebellaris lateralis superior, nucleus cerebellaris lateralis inferior; (2)Ascending,then tending to decline in purkinje cell layer; (3)Ascending in nucleus cerebellaris internus.These results reveled that Synaptophysin SVP_([38]) might be synthesized finally in Golgi complex, the peak of synapses formation in purkinje cell layer was in E_(20) or so and the development of synapses in different parts of cerebellum had an unbalanced characteristic in late embryo and early chicken.