The changes of T cell subsets in Mycoplasma pneumonia children with different chest X-ray manifestations

Objective: To explore the changes of T cell subsets in Mycoplasma pneumonia( MPP) children with different chest X-ray manifestations. Methods: One hundred and fifty-six children with MPP were divided into group A and group B according to the lobar pneumonia change. The chest X-ray in group A and group B showed the lobar pneumonia change and non-lobar pneumonia change,respectively. Sixty-two healthy children were set as the control group( group C). The T cell subsets in 3 groups were detected and analyzed. Results: Compared with group C,the levels of CD4+and CD4+/ CD8+in group A were significantly lower,while the level of CD8+in group A was significantly higher( P 0. 01). Conclusions: Immune injury plays an important role in the pathogenesis of MPP.The chest X-ray in older MPP children shows lobar pneumonia,which is strongly immunodepressed.