An observation of the curative effect of transcatheter arterial chemoembolization in patients with unresectable hepatocellular carcinoma

[Objective]To investigate the outcome following transcatheter arterial chemoembolization(TACE)and to identify the predictors of survival in patients with unresetable hepatocellular carcinoma(HCC).[Methods]Eighty HCC patients get clinical,biochemical and radiological examination befrom TACE.TACE was performed in those who fulfilled the inclusion criterial follow-up assessment was done with CT scan of the liver at 1,3,6,and 12months therapeutic effect tumor response and survival rate were estimated.Univariate analyses were done for determinations of survival.[Results]eighty patients were subjected to 163sessions of TACE.The Child's classification was:A 48patients(60%)and B 32patients(40%).Tumor size was≤5cm in 18(22.5%)patients,5-10cm in 42(52.5%)patients,and10cm in 20(25%)patients.12,56,9,3patients were subjected to 1,2,3,4sessions of TACE respectively,Overall survival rate was 71.3%,43.8%and 17.5%at 1,2and 3years,respectively.Tumor size energed as an important predictor of survival.Conclution:TACE offers a reasonable palliative therapy for HCC.Initial tumor size is an independent predictor of survival.