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2003•Tianjin Yike Daxue xuebaoRequires access

Significance of plasma tumor necrosis factor-α(TNF-α)level in septic shock

Bing Chen

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Abstract

Objective:To investigate the significance of plasma tumor necrosis factor-α(TNF-α)level in septic shock.Methods:ELISA methods were used to determine the TNF-αlevel in septic shock.Results:Plasma TNF-αlevels in the patients with septic shock were significantly higher than the levels in healthy subjects(P0.01),and high TNF-αlevels were found in nonsurvivors compared to survivors.Conclusion:TNF-αplays important role in sepˉtic shock.The assay of them may be helpful for evaluation of septic shock and prognosis.

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What this paper is about

Objective:To investigate the significance of plasma tumor necrosis factor-α(TNF-α)level in septic shock.Methods:ELISA methods were used to determine the TNF-αlevel in septic shock.Results:Plasma TNF-αlevels in the patients with septic shock were significantly higher than the levels in healthy subjects(P0.01),and high TNF-αlevels were found in nonsurvivors compared to survivors.Conclusion:TNF-αplays important role in sepˉtic shock.The assay of them may be helpful for evaluation of septic shock and prognosis.

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Available abstract

Objective:To investigate the significance of plasma tumor necrosis factor-α(TNF-α)level in septic shock.Methods:ELISA methods were used to determine the TNF-αlevel in septic shock.Results:Plasma TNF-αlevels in the patients with septic shock were significantly higher than the levels in healthy subjects(P0.01),and high TNF-αlevels were found in nonsurvivors compared to survivors.Conclusion:TNF-αplays important role in sepˉtic shock.The assay of them may be helpful for evaluation of septic shock and prognosis.

Key concepts: Septic shock, Tumor necrosis factor alpha, Shock (circulatory), Medicine, Tumor necrosis factor α, Necrosis, Internal medicine, Sepsis

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