Analysis of the efficacy and influencing factors of intracranial aneurysm embolization-induced oculomotor nerve palsy

Objective To observe the clinical efficacy and influencing factors of interventional intracranial aneurysm embolization-induced oculomotor nerve palsy.Methods The clinical data of 18 consecutive patients with intracranial aneurysmembolization-induced oculomotor nerve palsy were analyzed retrospectively. The relationships between the recovery of oculomotor palsy and the degree of preoperative palsy (complete, incomplete), time from onset to treatment (≤14d, 14d) , size of aneurism (≤7mm, 7mm) , with or without preoperative hemorrhage, and the compactness of embolization (complete, residual neck) were analyzed.All the patients were followed up for 24 months.Results ①All the aneurysms of 18 patients were embolized successfully.The aneurysms of the 12 patients were embolized completely, and 6 had residual necks.②The oculomotor palsy in 11 of the 18 patients recovered completely, 6 recovered partially.The total improving rate was 94.4% ; one patient with recurrence of the aneurysm did not showed any improvement.③There were no significant differences in the seriousness of preoperative oculomotor palsy, time from onset to treatment, size of aneurysm, with or without subarachnoid hemorrhage, and compactness of embolization on the recovery of oculomotor nerve palsy (all P 0.05) .Conclusion Aneurysm embolization may effectively improve aneurysm-induced oculomotor palsy.If no any improvement after embolization, recanalization of the aneurysm should be considered.