Study of blood pressure variation and related independent factors in patients with acute stroke

Objective To explore the blood pressure variation and influential factors in patients with acute stroke.Methods 342 consecutive inpatients admitted within the first 24 hours after the onset of stroke were studied,and the basic information were collected,the blood pressure values were monitored during the first 7 hospital days,graded the companion diseases,recorded the ways and the time of managing blood pressure.The data was analyzed with SAS statistic software.Results(1)Blood pressure elevated in initial stage of acute stroke,it distinctively decreased during the first 16 hours,especially in first 4 hours,and changed smoothly from 16 hours to 48 hours after admission,P0.05.(2)Blood pressure in acute stage of brain infarction was higher than that of cerebral hemorrhage.(3)Blood pressure of stroke patients was higher than that of patients without hypertension history in acute stage.(4)Blood pressure variation had no difference among five brain infarction subgroups.(5)Multiple linear regression analysis revealed that stroke type,history of hypertension and scores of companion diseases were positively related with mean blood pressure,while scores of anamnesis were negatively related with mean diastolic blood pressure(DBP)in patients with acute stroke.Conclusions Blood pressure usually elevate in patients with acute stroke,it decrease distinctively during the first 16 hours,and change smoothly from 16 hours to 48 hours after admission.Blood pressure is higher in those patients who are cerebral hemorrhage,who had hypertension previously and more companion diseases than others at acute stage of stroke.