Erythema multiforme drug eruption caused by oral carbamazepine

One 44-year-old female patient with lung cancer,multiple brain metastasis and secondary epilepsy was admitted in hospital.Carbamazepine tablet 0.1 g thrice daily,intravenous 20% mannitol,omeprazole and dexamethasone were administered.After 20 days,the patient developed the scattered rash in skin and ulcer in mouth,which was considered as allergic medicine rash related to carbamazepine.All drugs were withdrawn immediately,and the patient was given epinastine 20 mg once daily,ketotifen 1 mg twice daily and halcinonide liquid,triamcinolone acetonide acetate and miconazole nitrate neomycin sulfate cream and calamine lotion thrice daily for external use.Three days later,her symptoms got severer,and the erythema multiforme drug eruption was diagnosed.The patient was intravenously given aztreonam 1.5 g,azithromycin 0.5 g and methylprednisolone 40 mg twice daily.Two weeks later,the deglutition recovered,and the oral medication of hormone was changed.All the skin and the mucosa recovered in one month later,and the patient discharged from hospital.