DEPT-(90+45), A NEW SPECTRAL EDITING TECHNIQUE

A novel spectral editing technique, which can be referred to as DEPT (90+45), is described. It is modified from the DEPT 135 pulse sequence by substituting the 135° pulse by a 90° pulse and a 45° pulse. By employing different phase cycles, one can obtain methyl only spectrum and methylene only spectrum. The methyl only spectrum is completely free of residual methine and methylene signals. However, the methine only spectrum (DEPT 90) and the methylene only spectrum are interfered with substantial residual signals from not selected carbon proton groups. As a consequence, DEPT (90+45) can be very useful for spectral editing in one dimensional NMR spectroscopy.