Changes of Proximal Tubule Ultrastructure during the Process of Cat Kidney Preservation

During the process of off body kidney low temperature preservation, it is the key proceeding to remain the structure and function integrality of cells in vascular endothelium and tubule epithelium. The proximal tubule is the most important domain of glomerulum filtrate been reabsorbed inside the kidney. Because of the speciality of its ultrastructure, cells of the proximal tubule epithelium are sensitive to changes of surroundings while the kidney was in low temperature preserving.Off body cat kidneys had been preserved for 0, 24,48 and 72 hours, and the ultrastructure was determined with transmit electron microscope to inspect the dynamic process of function decline of the preserved kidney. The result illuminated that brush border of proximal tubule fell off, and re assemble to loops inside the tubule cavity. It indicated the block of renal tubule could be a vital reason of preserving kidney collapse.