2011•Zhongguo shiyan fangjixue zazhiRequires access

Influence of Dihuangyinzi on Learning and Memory and AChE,ChAT of Hippocampal in Chronic Cerebral Hypoperfusion Rats

Rui Yang

Abstract

Objective:To investigate influence of Dihuangyinzi on learning and memory and AChE,ChAT of Hippocampal in chronic cerebral hypoperfusion rats.Method:Using the model of chronic cerebral ischemia by two-vessel occlusion,Learning and memory memory improvement was measured by Morris water maze test in rats of chronic cerebral hypoperfusion of Dihuangyinzi,and AChE,ChAT content were measured in hippocampus of rats.Result:Compared with the control group,Morris water maze test,Dihuangyinzi group escape latency Shortened,the number of cross platform increased,AChE and ChAT Content in the hippocampus were significantly increased.Conclusion:Dihuangyinzi can improve learning and memory function in rats of chronic cerebral hypoperfusion,which may protect the cholinergic system.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Morris water navigation task, Hippocampal formation, Hippocampus, Aché, Choline acetyltransferase, Cerebral hypoperfusion, Psychology, Perfusion