Clinicalpathological analysis of salivary gland myoepithelioma in 19 cases

Objective To investigate the clinical pathological characteristics,immunophenotype,and differential diagnosis of the myoepithelioma of salivary gland.Methods The clinical and pathological data of 19 patients with myoepithelioma of salivary gland were analyzed by immunohistochemistry and clinical pathological characteristics.Results Of the salivary gland myoepithelioma,the diameters were between 1.2 cm and 5.0 cm,and 13 cases were occurred in the parotid gland,4 cases in the palate and 2 cases in the submandibular gland. The percentage of positive expression of Calponin,S100,SMA,CK and GFAP protein were 100%,94.7%,73.7%,94.7% and 78.9% respectively.Conclusion Myoepithelioma of salivary gland tumors are benign with atypical clinical manifestations. As the tumor cells form under microscope is complex and diverse,it is easily misdiagnosed. The morphology and immunnohistochemistry is very pivotal and useful for differential diagnosis of myoepithelioma.