ScholarLens Back to search
2012•Zhongguo xin yao zazhiRequires access

Optimization of extraction parameters of crocin from Gardeniae Fructus using response surface methodology

Fang Zhao

Open publisher page 0 citations

Abstract

Objectives: To optimize the process of extracting crocins from Gardenia Fructus.Methods: HPLC,central composite design and response surface methodology were used to optimize the process of crocin-1 and crocin-2 extraction.Results: The optimal extraction parameters were as follows: ethanol concentration,51%;extraction temperature,65 ℃ and extraction time,18 min.The deviations between the experimental results and predicted values of crocin-1 and crocin-2 rates were 1.51% and 1.38%,respectively.Conclusion: The extraction technology is reliable,reasonable and highly predictive.

About this research paper

What this paper is about

Objectives: To optimize the process of extracting crocins from Gardenia Fructus.Methods: HPLC,central composite design and response surface methodology were used to optimize the process of crocin-1 and crocin-2 extraction.Results: The optimal extraction parameters were as follows: ethanol concentration,51%;extraction temperature,65 ℃ and extraction time,18 min.The deviations between the experimental results and predicted values of crocin-1 and crocin-2 rates were 1.51% and 1.38%,respectively.Conclusion: The extraction technology is reliable,reasonable and highly predictive.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objectives: To optimize the process of extracting crocins from Gardenia Fructus.Methods: HPLC,central composite design and response surface methodology were used to optimize the process of crocin-1 and crocin-2 extraction.Results: The optimal extraction parameters were as follows: ethanol concentration,51%;extraction temperature,65 ℃ and extraction time,18 min.The deviations between the experimental results and predicted values of crocin-1 and crocin-2 rates were 1.51% and 1.38%,respectively.Conclusion: The extraction technology is reliable,reasonable and highly predictive.

Key concepts: Crocin, Response surface methodology, Extraction (chemistry), Chromatography, Central composite design, Chemistry, High-performance liquid chromatography, Biochemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Optimization of extraction parameters of crocin from Gardeniae Fructus using response surface methodology — Research Paper | ScholarLens