Studies on the repellent effects and toxicity of a novel mosquito-repellent paper

Objective: To investigate the effects and toxicity of a new mosquito repellent in wet paper,composed mainly of Deet(N,N-diethl-meta-toluamide).Methods: The protection time and the protected rate were observed after the paper was used on the human backhands and arms in laboratory and field.Its toxicity was tested in rats、guinea pigs and rabbits.Results: It showed that the protection time against mosquitoes was 5h in laboratory while more than 6h in field.Oral and dermal LD50 were higher than 5g·kg and 2.15g·kg respectively in rats,indicating the repellent paper is a kind of low toxic product;it has no dermal stimulation and has moderate stimulation on eyes in rabbits;it has no allergic symptom in guinea pigs.Conclusion: The paper shows good repellency against mosquitoes and safe for human use.