Molecular Regulation of Mammalian Folliculogenesis and Oogenesis

Mammalian folliculogenesis and oogenesis research is an important part of the developmental biology.In this paper,the progression of mammalian folliculogenesis and oogenesis,many key genes such as gdf9,c-kit,BMP4 and TGF involved in the cellular differentiation proceeding from primordial germ cells to oocytes,the interrelationship between oocyte and granulose cells within the growing follicles,the advance of mammalian oogenesis in vitro were reviewed.Molecular regulation processes of oogenesis provide a clue to mechanism of mammalian oogenesis from primordial germ cells to oocytes.