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Studies on Content Measuring of Magnolol and Honokiol in Magnoliae Officinalis Pill

Xueping Wang

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Abstract

The method of measuring the content of magnolol and honokiol in Magnoliae Officinalis Pell is established.Method:Adopting HPLC to measure the content of magnolol and honlkiol.Result:The linear scope of measuring method of content of magnolol and honokiol is 0.488~2.440μg(Chi-Square:27.44) and 0.362~1.810μg(Chi-Square:36.07)respectively.The average recovery ratio is 97.0%,RSD=1.3%(n=5) and 96.8%,RSD=1.4%(n=5)respectively.Conclusion:The method established is accurate and practical with good repeatability.It can be taken as the quality norm for controlling the content of officinal magnolia bark in Magnoliae Officinalis Pill.

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What this paper is about

The method of measuring the content of magnolol and honokiol in Magnoliae Officinalis Pell is established.Method:Adopting HPLC to measure the content of magnolol and honlkiol.Result:The linear scope of measuring method of content of magnolol and honokiol is 0.488~2.440μg(Chi-Square:27.44) and 0.362~1.810μg(Chi-Square:36.07)respectively.The average recovery ratio is 97.0%,RSD=1.3%(n=5) and 96.8%,RSD=1.4%(n=5)respectively.Conclusion:The method established is accurate and practical with good repeatability.It can be taken as the quality norm for controlling the content of officinal magnolia bark in Magnoliae Officinalis Pill.

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Available abstract

The method of measuring the content of magnolol and honokiol in Magnoliae Officinalis Pell is established.Method:Adopting HPLC to measure the content of magnolol and honlkiol.Result:The linear scope of measuring method of content of magnolol and honokiol is 0.488~2.440μg(Chi-Square:27.44) and 0.362~1.810μg(Chi-Square:36.07)respectively.The average recovery ratio is 97.0%,RSD=1.3%(n=5) and 96.8%,RSD=1.4%(n=5)respectively.Conclusion:The method established is accurate and practical with good repeatability.It can be taken as the quality norm for controlling the content of officinal magnolia bark in Magnoliae Officinalis Pill.

Key concepts: Magnolol, Honokiol, Magnolia officinalis, Officinalis, Traditional medicine, Repeatability, Chromatography, Chemistry

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