Changes of the white blood cell(WBC)count and its clinical significance in early stage of acute cerebral infarction

Objective To explore the correlation between peripheral WBC count in acute cerebral infarction and the development and prognosis of the disease.Methods Retrospective statistics of 2?812 severe cerebral infarction patients were carried out.The patients were divided into two groups according to WBC count:those with WBC count higher than 10×10 9/L were assigned to abnormal group and those with WBC count lower than 10×10 9/L were assigned to normal group.WBC count at three stages (1～3,4～6,7～10 d) was calculated at the same time with death rate and consciousness.An analysis of the WBC count of the dead and the survivors was made.Results The fatality rate of the abnormal group was obviously higher than that of the normal group.The fatality rate increased with the rise of WBC count,which was obviously higher in the dead than in the survivors.There was correlation between the inrease in WBC count and the severity of disorder of consciousness state.Conclusions It is the stress after brain injury to a certain severity that leads to the increase in WBC count,which is the important reason for the serious condition and poor diagnosis of the patient. As an obvious correlation is established between WBC count and the outcome,WBC count can be a simple and easy predictor of the prognosis of cerebrovascular diseases.