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Relationship between pregnant women with ABO blood group incompatibility and hemolytic disease of newborn

HU Yong-mei

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Abstract

Objective To study the relationship between serum antibody IgG level of pregnant women with type O and hemolytic disease of newborn(HDN). Methods Prenatal immunohematological tests were done for 754 pregnant women with type O whose husbands were not type O. Meanwhile, HDN immunohematological tests were also done for the newborns whose mothers' antibody IgG titer was ≥64. Results Among the 754 pregnant women, there were 287 with type O and antibody IgG titer ≥64. Of these women' newborns,31 suffered from HDN. Conclusion The incidence of HDN is positively correlated to the level of serum antibody IgG in pregnant women.

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What this paper is about

Objective To study the relationship between serum antibody IgG level of pregnant women with type O and hemolytic disease of newborn(HDN). Methods Prenatal immunohematological tests were done for 754 pregnant women with type O whose husbands were not type O. Meanwhile, HDN immunohematological tests were also done for the newborns whose mothers' antibody IgG titer was ≥64. Results Among the 754 pregnant women, there were 287 with type O and antibody IgG titer ≥64. Of these women' newborns,31 suffered from HDN. Conclusion The incidence of HDN is positively correlated to the level of serum antibody IgG in pregnant women.

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Available abstract

Objective To study the relationship between serum antibody IgG level of pregnant women with type O and hemolytic disease of newborn(HDN). Methods Prenatal immunohematological tests were done for 754 pregnant women with type O whose husbands were not type O. Meanwhile, HDN immunohematological tests were also done for the newborns whose mothers' antibody IgG titer was ≥64. Results Among the 754 pregnant women, there were 287 with type O and antibody IgG titer ≥64. Of these women' newborns,31 suffered from HDN. Conclusion The incidence of HDN is positively correlated to the level of serum antibody IgG in pregnant women.

Key concepts: ABO blood group system, Medicine, Blood type (non-human), Titer, Antibody, Incidence (geometry), Hemolytic disease of the newborn (ABO), Pregnancy

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