Left ventricular remodeling and systolic performance after valve replacement for valvular heart disease with giant left ventricle

Objective To observe the left ventricular remodeling and evaluate its relationship with left ventricular systolic performance after valve replacement for valvular heart disease with giant left ventricle.Methods 33 patients with valvular heart disease and giant left ventricle after valve replacement was retrospectively reviewed.The results of ultrasonic cardiography(UCG) and the changes of cardiac function before and after operation were compared.Combined mitral and aortic valve replacement was performed in 8 cases,mitral valve replacement in 4 cases,aortic valve replacement and ventricular septal defect neoplasty in 2 cases,aortic valve replacement andcoronary artery bypass graft in 2 cases,Bental's operation in 5 cases,tricuspid valve annuloplasty in 7 cases.Results The value of left ventricular end-diastolic dimension(LVEDD),left ventricular end-systolic dimension(LVESD),The value of left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular ejection fraction(LVEF),left ventricular fractional shortening(LVFS) in 1 and 3 months after operation were more decreased than those before operation(P0.05).Conclusion Early operation are in favor of left ventricular geometry reversal and systolic function improvement for patients with GLV.The protection for cardiac function should be carefully taken in order to prevent the occurrence of complication after operation.